diff --git a/net/tcp/tcp_send_buffered.c b/net/tcp/tcp_send_buffered.c
index 9035243d575..2387da4a246 100644
--- a/net/tcp/tcp_send_buffered.c
+++ b/net/tcp/tcp_send_buffered.c
@@ -281,7 +281,6 @@ static inline void send_ipselect(FAR struct net_driver_s *dev,
     {
       /* Select the IPv6 domain */
 
-      DEBUGASSERT(conn->domain == PF_INET6);
       tcp_ipv6_select(dev);
     }
 }
@@ -361,7 +360,6 @@ static uint16_t psock_send_eventhandler(FAR struct net_driver_s *dev,
       if (conn->domain == PF_INET)
 #endif
         {
-          DEBUGASSERT(IFF_IS_IPv4(dev->d_flags));
           tcp = TCPIPv4BUF;
         }
 #endif /* CONFIG_NET_IPv4 */
@@ -371,7 +369,6 @@ static uint16_t psock_send_eventhandler(FAR struct net_driver_s *dev,
       else
 #endif
         {
-          DEBUGASSERT(IFF_IS_IPv6(dev->d_flags));
           tcp = TCPIPv6BUF;
         }
 #endif /* CONFIG_NET_IPv6 */
diff --git a/net/tcp/tcp_send_unbuffered.c b/net/tcp/tcp_send_unbuffered.c
index 90af5c25b9d..efbd7f6c5a9 100644
--- a/net/tcp/tcp_send_unbuffered.c
+++ b/net/tcp/tcp_send_unbuffered.c
@@ -139,7 +139,6 @@ static inline void tcpsend_ipselect(FAR struct net_driver_s *dev,
     {
       /* Select the IPv6 domain */
 
-      DEBUGASSERT(conn->domain == PF_INET6);
       tcp_ipv6_select(dev);
     }
 }
@@ -220,7 +219,6 @@ static uint16_t tcpsend_eventhandler(FAR struct net_driver_s *dev,
       if (conn->domain == PF_INET)
 #endif
         {
-          DEBUGASSERT(IFF_IS_IPv4(dev->d_flags));
           tcp = TCPIPv4BUF;
         }
 #endif /* CONFIG_NET_IPv4 */
@@ -230,7 +228,6 @@ static uint16_t tcpsend_eventhandler(FAR struct net_driver_s *dev,
       else
 #endif
         {
-          DEBUGASSERT(IFF_IS_IPv6(dev->d_flags));
           tcp = TCPIPv6BUF;
         }
 #endif /* CONFIG_NET_IPv6 */
diff --git a/net/tcp/tcp_sendfile.c b/net/tcp/tcp_sendfile.c
index be48a1fe369..cff780382e3 100644
--- a/net/tcp/tcp_sendfile.c
+++ b/net/tcp/tcp_sendfile.c
@@ -170,7 +170,6 @@ static uint16_t sendfile_eventhandler(FAR struct net_driver_s *dev,
       if (IFF_IS_IPv6(dev->d_flags))
 #endif
         {
-          DEBUGASSERT(conn->domain == PF_INET6);
           tcp = TCPIPv6BUF;
         }
 #endif /* CONFIG_NET_IPv6 */
@@ -180,9 +179,6 @@ static uint16_t sendfile_eventhandler(FAR struct net_driver_s *dev,
       else
 #endif
         {
-#if defined(CONFIG_NET_IPv4) && defined(CONFIG_NET_IPv6)
-          DEBUGASSERT(conn->domain == PF_INET);
-#endif
           tcp = TCPIPv4BUF;
         }
 #endif /* CONFIG_NET_IPv4 */
diff --git a/net/udp/udp_sendto_buffered.c b/net/udp/udp_sendto_buffered.c
index 0ef2713252c..0f48147b500 100644
--- a/net/udp/udp_sendto_buffered.c
+++ b/net/udp/udp_sendto_buffered.c
@@ -208,7 +208,6 @@ static inline void sendto_ipselect(FAR struct net_driver_s *dev,
     {
       /* Select the IPv6 domain */
 
-      DEBUGASSERT(conn->domain == PF_INET6);
       udp_ipv6_select(dev);
     }
 }
diff --git a/net/udp/udp_sendto_unbuffered.c b/net/udp/udp_sendto_unbuffered.c
index 4a4da2a6eb1..b4bf0da9695 100644
--- a/net/udp/udp_sendto_unbuffered.c
+++ b/net/udp/udp_sendto_unbuffered.c
@@ -117,7 +117,6 @@ static inline void sendto_ipselect(FAR struct net_driver_s *dev,
     {
       /* Select the IPv6 domain */
 
-      DEBUGASSERT(conn->domain == PF_INET6);
       udp_ipv6_select(dev);
     }
 }