diff --git a/arch/sim/src/CMakeLists.txt b/arch/sim/src/CMakeLists.txt
index 57c8c6e04b8..1a9a5bd0182 100644
--- a/arch/sim/src/CMakeLists.txt
+++ b/arch/sim/src/CMakeLists.txt
@@ -30,3 +30,7 @@ if(NOT CONFIG_BUILD_FLAT)
   target_include_directories(arch_interface BEFORE PUBLIC ${CONFIG_ARCH_CHIP}
                                                           common)
 endif()
+
+if(CONFIG_FS_LARGEFILE)
+  target_compile_options(nuttx PRIVATE -D_FILE_OFFSET_BITS=64)
+endif()