diff --git a/arch/arm/src/stm32f7/stm32_otgdev.c b/arch/arm/src/stm32f7/stm32_otgdev.c
index f06175cb5bf..54a0232cdfe 100644
--- a/arch/arm/src/stm32f7/stm32_otgdev.c
+++ b/arch/arm/src/stm32f7/stm32_otgdev.c
@@ -4230,7 +4230,10 @@ static void stm32_epin_disable(FAR struct stm32_ep_s *privep)
 
   /* Clear the EPDISD interrupt indication */
 
-  stm32_putreg(OTG_DIEPINT_EPDISD, stm32_getreg(regaddr));
+  regval = stm32_getreg(regaddr);
+  regval |= OTG_DIEPINT_EPDISD;
+  stm32_putreg(OTG_DIEPINT_EPDISD, regaddr);
+
 
   /* Flush any data remaining in the TxFIFO */