diff --git a/esphome/components/cc1101/cc1101.cpp b/esphome/components/cc1101/cc1101.cpp
index f2b7451721a..c231f314cc2 100644
--- a/esphome/components/cc1101/cc1101.cpp
+++ b/esphome/components/cc1101/cc1101.cpp
@@ -102,6 +102,8 @@ CC1101Component::CC1101Component() {
   memset(this->pa_table_, 0, sizeof(this->pa_table_));
 }
 
+void IRAM_ATTR CC1101Component::gpio_intr(CC1101Component *arg) { arg->enable_loop_soon_any_context(); }
+
 void CC1101Component::setup() {
   this->spi_setup();
   this->cs_->digital_write(true);
@@ -148,11 +150,12 @@ void CC1101Component::setup() {
   // Defer pin mode setup until after all components have completed setup()
   // This handles the case where remote_transmitter runs after CC1101 and changes pin mode
   if (this->gdo0_pin_ != nullptr) {
-    this->defer([this]() { this->gdo0_pin_->pin_mode(gpio::FLAG_INPUT); });
-  }
-
-  if (this->state_.PKT_FORMAT != static_cast<uint8_t>(PacketFormat::PACKET_FORMAT_FIFO)) {
-    this->disable_loop();
+    this->defer([this]() {
+      this->gdo0_pin_->pin_mode(gpio::FLAG_INPUT);
+      if (this->state_.PKT_FORMAT == static_cast<uint8_t>(PacketFormat::PACKET_FORMAT_FIFO)) {
+        this->gdo0_pin_->attach_interrupt(&CC1101Component::gpio_intr, this, gpio::INTERRUPT_RISING_EDGE);
+      }
+    });
   }
 }
 
@@ -164,6 +167,7 @@ void CC1101Component::call_listeners_(const std::vector<uint8_t> &packet, float
 }
 
 void CC1101Component::loop() {
+  this->disable_loop();
   if (this->state_.PKT_FORMAT != static_cast<uint8_t>(PacketFormat::PACKET_FORMAT_FIFO) || this->gdo0_pin_ == nullptr ||
       !this->gdo0_pin_->digital_read()) {
     return;
@@ -244,6 +248,7 @@ void CC1101Component::begin_tx() {
   this->write_(Register::PKTCTRL0, 0x32);
   ESP_LOGV(TAG, "Beginning TX sequence");
   if (this->gdo0_pin_ != nullptr) {
+    this->gdo0_pin_->detach_interrupt();
     this->gdo0_pin_->pin_mode(gpio::FLAG_OUTPUT);
   }
   // Transition through IDLE to bypass CCA (Clear Channel Assessment) which can
@@ -673,10 +678,12 @@ void CC1101Component::set_packet_mode(bool value) {
     this->state_.GDO0_CFG = 0x0D;
   }
   if (this->initialized_) {
-    if (value) {
-      this->enable_loop();
-    } else {
-      this->disable_loop();
+    if (this->gdo0_pin_ != nullptr) {
+      if (value) {
+        this->gdo0_pin_->attach_interrupt(&CC1101Component::gpio_intr, this, gpio::INTERRUPT_RISING_EDGE);
+      } else {
+        this->gdo0_pin_->detach_interrupt();
+      }
     }
     this->write_(Register::PKTCTRL0);
     this->write_(Register::PKTCTRL1);
diff --git a/esphome/components/cc1101/cc1101.h b/esphome/components/cc1101/cc1101.h
index 2efd9e082d5..68d81ac8f3c 100644
--- a/esphome/components/cc1101/cc1101.h
+++ b/esphome/components/cc1101/cc1101.h
@@ -93,6 +93,7 @@ class CC1101Component : public Component,
 
   // GDO pin for packet reception
   InternalGPIOPin *gdo0_pin_{nullptr};
+  static void IRAM_ATTR gpio_intr(CC1101Component *arg);
 
   // Packet handling
   void call_listeners_(const std::vector<uint8_t> &packet, float freq_offset, float rssi, uint8_t lqi);
diff --git a/esphome/components/sx126x/sx126x.cpp b/esphome/components/sx126x/sx126x.cpp
index ec62fad10af..6ea09e3a9e8 100644
--- a/esphome/components/sx126x/sx126x.cpp
+++ b/esphome/components/sx126x/sx126x.cpp
@@ -104,11 +104,17 @@ void SX126x::write_register_(uint16_t reg, uint8_t *data, uint8_t size) {
   delayMicroseconds(SWITCHING_DELAY_US);
 }
 
+void IRAM_ATTR SX126x::gpio_intr(SX126x *arg) { arg->enable_loop_soon_any_context(); }
+
 void SX126x::setup() {
   // setup pins
   this->busy_pin_->setup();
   this->rst_pin_->setup();
   this->dio1_pin_->setup();
+  if (this->dio1_pin_->is_internal()) {
+    static_cast<InternalGPIOPin *>(this->dio1_pin_)
+        ->attach_interrupt(&SX126x::gpio_intr, this, gpio::INTERRUPT_RISING_EDGE);
+  }
 
   // start spi
   this->spi_setup();
@@ -348,6 +354,9 @@ void SX126x::call_listeners_(const std::vector<uint8_t> &packet, float rssi, flo
 }
 
 void SX126x::loop() {
+  if (this->dio1_pin_->is_internal()) {
+    this->disable_loop();
+  }
   if (!this->dio1_pin_->digital_read()) {
     return;
   }
diff --git a/esphome/components/sx126x/sx126x.h b/esphome/components/sx126x/sx126x.h
index a758d637955..edc00e3727e 100644
--- a/esphome/components/sx126x/sx126x.h
+++ b/esphome/components/sx126x/sx126x.h
@@ -3,6 +3,7 @@
 #include "esphome/components/spi/spi.h"
 #include "esphome/core/automation.h"
 #include "esphome/core/component.h"
+#include "esphome/core/hal.h"
 #include "sx126x_reg.h"
 #include <utility>
 #include <vector>
@@ -100,6 +101,7 @@ class SX126x : public Component,
   Trigger<std::vector<uint8_t>, float, float> *get_packet_trigger() { return &this->packet_trigger_; }
 
  protected:
+  static void IRAM_ATTR gpio_intr(SX126x *arg);
   void configure_fsk_ook_();
   void configure_lora_();
   void set_packet_params_(uint8_t payload_length);
diff --git a/esphome/components/sx127x/sx127x.cpp b/esphome/components/sx127x/sx127x.cpp
index 83be96767a4..2b13efb38da 100644
--- a/esphome/components/sx127x/sx127x.cpp
+++ b/esphome/components/sx127x/sx127x.cpp
@@ -53,6 +53,8 @@ void SX127x::write_fifo_(const std::vector<uint8_t> &packet) {
   this->disable();
 }
 
+void IRAM_ATTR SX127x::gpio_intr(SX127x *arg) { arg->enable_loop_soon_any_context(); }
+
 void SX127x::setup() {
   // setup reset
   this->rst_pin_->setup();
@@ -60,6 +62,7 @@ void SX127x::setup() {
   // setup dio0
   if (this->dio0_pin_) {
     this->dio0_pin_->setup();
+    this->dio0_pin_->attach_interrupt(&SX127x::gpio_intr, this, gpio::INTERRUPT_RISING_EDGE);
   }
 
   // start spi
@@ -313,6 +316,7 @@ void SX127x::call_listeners_(const std::vector<uint8_t> &packet, float rssi, flo
 }
 
 void SX127x::loop() {
+  this->disable_loop();
   if (this->dio0_pin_ == nullptr || !this->dio0_pin_->digital_read()) {
     return;
   }
@@ -386,11 +390,6 @@ void SX127x::set_mode_(uint8_t modulation, uint8_t mode) {
       return;
     }
   }
-  if (mode == MODE_RX && (modulation == MOD_LORA || this->packet_mode_)) {
-    this->enable_loop();
-  } else {
-    this->disable_loop();
-  }
 }
 
 void SX127x::set_mode_rx() {
diff --git a/esphome/components/sx127x/sx127x.h b/esphome/components/sx127x/sx127x.h
index be7b6d8d9f8..76f942fddac 100644
--- a/esphome/components/sx127x/sx127x.h
+++ b/esphome/components/sx127x/sx127x.h
@@ -4,6 +4,7 @@
 #include "esphome/components/spi/spi.h"
 #include "esphome/core/automation.h"
 #include "esphome/core/component.h"
+#include "esphome/core/hal.h"
 #include <vector>
 
 namespace esphome {
@@ -86,6 +87,7 @@ class SX127x : public Component,
   Trigger<std::vector<uint8_t>, float, float> *get_packet_trigger() { return &this->packet_trigger_; }
 
  protected:
+  static void IRAM_ATTR gpio_intr(SX127x *arg);
   void configure_fsk_ook_();
   void configure_lora_();
   void set_mode_(uint8_t modulation, uint8_t mode);